Thursday, April 8, 2021

NIH-NIAID Tropical Medicine Research Centers (U01 Clinical Trial Not Allowed) RFA-AI-21-004

Funding Opportunity Announcement (FOA) Number: RFA-AI-21-004

This FOA solicits research applications focused on the etiology, epidemiology, pathogenesis, clinical manifestations, diagnosis, prevention, treatment and control of select Neglected Tropical Diseases (NTDs) in endemic areas. The Tropical Medicine Research Centers (TMRCs) are intended to advance NIAID’s global research effort by targeting research endeavors to: develop novel diagnostic, prevention and therapeutic strategies adapted for the unique needs of low and middle-income countries (LMICs), as classified by the World Bank; create and sustain in-country research capacity; stimulate scientific collaboration and global partnerships; provide opportunities for junior and early-stage investigators to conduct research on NTDs; and facilitate sample sharing to support translational research to develop or evaluate new drugs, diagnostics, vaccines, therapeutics, and/or vector control strategies.

Eligibility

Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.

Key Dates:

Open Date (Earliest Submission Date): May 18, 2021

Letter of Intent Due Date(s): 30 days prior to the application due date

Application due date: June 18, 2021

Award Budget:  $500,000 per year in direct costs

Funds Available and Anticipated Number of Awards: NIAID intends to commit $3,800,000 in FY 2022 to fund four to six awards.

This FOA will not support the following types of research projects. Applications that propose research projects in these areas will be considered non-responsive and will not be reviewed.

  • Research on NTDs that does not require access to human subjects or specimens from disease-endemic sites in LMICs;
  • Research that is not focused on the following pathogens, except in the context of co-infections or non-NTD outcomes as a result of anti-NTD interventions: schistosomiasis, hookworm infection, ascariasis, leishmaniasis, trypanosomiasis, Chagas’ Disease, trichuriasis, leprosy, lymphatic filariasis, trachoma, onchocerciasis, dracunculiasis, Buruli ulcer, echinococcosis, taeniasis and cysticercosis, and food-borne trematodiases.
  • Research that is not focused on: genomics, epidemiology, diagnostics, transmission, immunology, and/or pathogenesis
  • Research on Select Agents (see: http://www.selectagents.gov/SelectAgentsandToxinsList.html and accompanying regulations: https://www.selectagents.gov/regulations/index.htm).
  • Research on HIV/SIV
  • Clinical trials