Monday, July 7, 2014

NIH/NIAID Development of Novel Therapeutics for Select Anaerobic Protozoa (R21/R33)

Funding Opportunity Announcement (FOA) Number RFA-AI-14-015

Funding Opportunity Purpose 
The purpose of this FOA is to solicit applications to support early stage translational research focused on the development of novel therapeutics against select anaerobic protozoal pathogens.

Treatment of infectious diseases caused by anaerobic protozoal pathogens is compromised by limited effective therapeutic options and/or development of resistance. There is a critical need for development of new therapeutic approaches to treat these clinically-important diseases, including novel approaches such as small molecule antimicrobials and/or adjunctive therapeutics targeting resistance mechanisms. This initiative encourages the discovery, preclinical development and/or validation of novel interventions for the treatment of infectious diseases caused by select anaerobic protozoa (amebiasis, giardiasis, trichomoniasis and diseases caused by free-living amoebae).

Open Date (Earliest Submission Date) September 30, 2014

Letter of Intent Due Date September 30, 2014

Application Due Date October 30, 2014, by 5:00 PM local time of applicant organization

Earliest Start Date July 2015

Foreign Institutions Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.

Activity Code R21/R33 Phased Innovation Award

Award Budget
R21 Phase: 2 two years
Direct costs are limited to $275,000 over the 2 years; a maximum of $200,000 in direct costs is allowed in any single year.

R33 Phase: Direct costs are limited to $300,000 per year and cannot exceed 3 years. 

Consortia F&A (Indirect Costs/Overheads) are not included in the direct costs. 

The NIAID anticipates that a maximum of 50% of the funded R21 phase awards will progress to the R33 award.

Letter of Intent
Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review.
By the date listed in Part 1. Overview Information, prospective applicants are asked to submit a letter of intent that includes the following information:
·         Descriptive title of proposed activity
·         Name(s), address(es), and telephone number(s) of the PD(s)/PI(s)
·         Names of other key personnel
·         Participating institution(s)
·         Number and title of this funding opportunity
The letter of intent should be sent to:
Annie Walker-Abbey, PhD
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 301-451-2671
Fax: 301-480-2408
Email: aabbey@niaid.nih.gov

If you want more information about the grant opportunity or need help with your application, please contact us at the Office of Research Services:


Tel; 023069125 or 023069126