Friday, October 5, 2012

NIH Grant: Immunity in the Elderly (R01) (RFA-AI-12-038)

Immunity in the Elderly

The National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Aging (NIA) invite applications to define the mechanisms for induction, development, and maintenance of protective immunity in the elderly in response to infections with or vaccinations against NIAID Emerging and Re-emerging Infectious Diseases

  The goal of this FOA is to develop a better understanding of the immune mechanisms involved during the aging process that contribute to impaired immune responses resulting in severe infections and dampened responses to vaccines in this population.  This FOA requires human studies, to gain insights into immune changes in elderly individuals.  Thus, at least one aim of the project must focus fully on human studies; appropriately justified animal work may be included in additional aims to conduct mechanistic studies that are not possible in humans. 

Funding Opportunity Announcement (FOA) Number
RFA-AI-12-038
Open Date (Earliest Submission Date)
January 18, 2013  
Letter of Intent Due Date
January 18, 2013  
Application Due Date(s)
February 20, 2013
Funds Available and Anticipated Number of Awards
The following NIH components intend to commit the following amounts in FY2014:

NIAID, $4 million, 8-10 awards
NIA, $2 million, 4-5 awards   
Award Budget
Direct costs for each application are expected to be $300,000 or less per year, plus appropriate F&A costs. Budgets should be commensurate with the proposed studies and adequately justified.  
Award Project Period
Scope of the proposed project should determine the project period.  The maximum period is 5 years. 

The original announcement and further details are available at:

http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-12-038.html