Wednesday, February 8, 2012

Resource Access for the Bridging Interventional Development Gaps Program (X01)


Resource Access for the Bridging Interventional Development Gaps Program (X01)

The high cost of translating therapeutic discoveries into clinically-available agents can deter the development of promising therapeutics. When private sector resources are limited, BrIDGs’ in-kind services could help researchers span the gap between the preclinical and clinical stages of therapy development and continue to evaluate agents that may improve the standard of care for patients with a variety of diseases and disorders. The purpose of this Funding Opportunity Announcement (FOA) is to invite investigators to apply for access to government-funded contract resources needed for the preclinical development of therapeutic agents.
Applications are accepted for the development of the following therapeutic agents:


  • Small molecules
  • Peptides
  • Oligonucleotides
  • Gene vectors
  • Recombinant proteins
  • Monoclonal antibodies


Potential therapies for any disease or disorder may be submitted. Vaccines, devices and diagnostic agents are ineligible for the program. Only lead agents with demonstrated pharmacological activity in an appropriate disease model will be considered for development.


Application open date: March 3, 2012