The R21 mechanism is intended to encourage new exploratory and developmental research projects.
All subjects and disciplines are eligible, but the research must be high-risk, high-impact, and highly innovative.
For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
This grant is worth $275,000 over 2 years. The nearest deadline is 16 February 2012
For more information, see: http://grants.nih.gov/grants/guide/pa-files/PA-10-069.html