NIH Therapeutics for Neurotropic Biodefense Toxins and Pathogens (R21/R33)

This NIH grants seeks studies addressing pathogens such as rabies and Japanese encephalitis virus in the following focus areas:

• development of improved neurotropic therapeutic delivery technologies;
• development or optimization of candidate therapeutic delivery platforms;
• identification and validation of new therapeutic targets such as receptors that enable toxins or pathogens to cross the blood-brain barrier or enter neurons;
• research utilizing genomics, proteomics, metabolomics, and/or bioinformatics to identify therapeutic targets;
• screening and identification of new therapeutic agents directed against neurotropic toxins or pathogens;
• preclinical efficacy and/or toxicity testing of candidate therapeutics; and lead candidate optimization.

Responsive applications must address discovery and/or development of new therapeutics against one or more of the following neurotropic agents.

This grant is worth $275,000 over the first two years, and then $300,000 per year for three additional years.

Please see the following link for more information:
http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-11-027.html


The deadline is 24 October 2011