International Research in Infectious Diseases, including AIDS (R01)

Funding Opportunity Announcement (FOA) Number: PA-17-142

This Funding Opportunity Announcement (FOA) encourages applications from organizations/institutions in eligible foreign countries that propose research related to infectious diseases that are of interest/importance to that country.

Eligibility

Foreign Institutions

Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Key Dates

Open Date (Earliest Submission Date)    April 22, 2017

Letter of Intent Due Date(s)                    April 22, 2017 

Application Due Date(s)                         May 22, 2017

AIDS Application Due Date(s)               August 22, 2017

Local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

For more details: https://grants.nih.gov/grants/guide/pa-files/PAR-17-142.html

If you have any queries and if you are interested in applying for this research funding opportunity, please contact us at the Office of Research Services and we will be pleased to provide further information and support 

e-mail: tropmed.mahidol.univ@gmail.com

MMV 15th Call for proposals

All applications using the specified templates should be sent electronically to proposals@mmv.org by 12 noon CET, Friday, 24 March 2017.  

MMV welcomes proposals in the following three areas:

1. Compounds addressing the key priorities of the malaria eradication agenda

Novel families of molecules in the hit-to-lead or lead optimization stages are sought without G6PD deficiency liabilities that either:

• kill or reactivate hypnozoites for use as part of a P. vivax radical cure; or  
• have activity against sexual stage V gametocytes and evidence of transmission blocking in SMFA.

2. Compounds with activity against asexual liver and/or blood stages

Novel chemical series with EC50<500nM and which have one or more of the following key features:

• A known, novel mechanism of action;
• An inability to select resistant mutants in vitro;
• Activity at more than one life-cycle stage;
• A long half-life (ideally >4h in rodents) and confirmed in vivo efficacy.
• For advanced series, we are seeking novel compounds with, ideally, a predicted human half-life >100h and a predicted oral single human dose <500mg or an i.m. dose that can be administered in <0.5mL and sufficient for up to 3 months’ protection in humans.

3. Novel approaches for screening

To help identify new phenotypic and/ or target based hits, as well as confirm activity of MMV compounds on all human malaria asexual blood stages, new screening proposals are sought amongst the three categories below:

• Validated Plasmodium target-based assays, ideally with evidence of target essentiality beyond asexual blood stages. Biological validation should be supported by a biological target based screening assay suited for identification of novel chemical series. 
• Novel whole cell phenotypic screening paradigms to potentially identify new relevant chemistry.
• Asexual blood stage assays for vivax, malariae and ovale malaria.

MMV also welcomes requests for support to investigate the mechanism of action of compounds

More details here. 

Collaborative Awards in Science 

Collaborative Awards promote the development of new ideas and speed the pace of discovery. We fund teams of researchers, consisting of independent research groups, to work together on the most important scientific problems that can only be solved through collaborative efforts.

Career stage:

Intermediate, Senior

Where your host organisation is based: UK, Republic of Ireland, Low- and middle-income countries

Type of researcher:

Basic, Clinical, Public health

Level of funding:

Up to £4 million

Duration of funding:

Up to 5 years

What we're looking for:

Your proposal should describe a significant piece of work that addresses the most important questions, in an area relevant to the mission of the Wellcome Trust. You should be able to demonstrate why the scientific problem you are tackling can only be solved through an integrated, collaborative team effort. We encourage interdisciplinary research collaborations, although they are not essential. We also encourage applications that propose interdisciplinary research across our Science, Humanities and Social Science and Innovations teams

Who can apply:

Collaborative Awards are for teams of researchers bringing together the relevant expertise and experience to address the most important scientific problems.  

Each applicant must be essential to the proposed collaborative research and have:

• Proven research expertise and experience in their field.
• An academic or research post (or equivalent).
• A salary for the duration of the award period. If this is not in place, your employing organisation must provide a guarantee of salary support for the duration of the award.

Members of the team must have proven experience in collaborative research and consist of independent research groups. Team size will depend on the proposed research, but should generally have more than two applicants, and no more than seven. Teams may be based in the same or in different organisations, and must bring different expertise or disciplines to the research question. 

Our support includes research expenses directly related to your proposal. We don't provide funds for directly allocated or indirect costs 

Link to call https://wellcome.ac.uk/funding/collaborative-awards-science

Link to application system https://wtgrants.wellcome.ac.uk/Login.aspx?ReturnUrl=%2f

View of full application form (following successful preliminary application) https://wellcome.ac.uk/sites/default/files/sample-full-app-form-collaborative-awards-science-2016-August.pdf

Strengthening the HIV Pre-Exposure Prophylaxis (PrEP) Care Continuum through Behavioral, Social, and Implementation Science (R21)

Funding Opportunity Announcement (FOA) Number PA-17-103

This Funding Opportunity Announcement (FOA) encourages behavioral, social, and implementation science research designed to (a) identify gaps in the HIV pre-exposure prophylaxis (PrEP) care continuum and associated determinants; (b) develop and test interventions to strengthen PrEP delivery, use, and outcomes; and (c) reduce racial/ethnic and age-related disparities in PrEP uptake and use.

This FOA uses the R21 grant mechanism while companion FOA PA-17-104 uses the R01 mechanism. High risk/high payoff projects that lack preliminary data are appropriate for the R21 mechanism, while applicants with preliminary data who propose longitudinal analyses and/or large scale projects may consider the R01 mechanism.

Eligibility

Foreign Institutions

Non-domestic (non-U.S.) Entities (Foreign Institutions) are  eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are  eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are  allowed.

Eligible Individuals (Program Director/Principal Investigator)

Any individual(s) with the skills, knowledge and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.

Key Dates

Open Date (Earliest Submission Date)    April 7, 2017

For more details, click here: https://grants.nih.gov/grants/guide/pa-files/PA-17-103.html 

Vaccine development against prioritized epidemic infectious diseases

CEPI, the Coalition for Epidemic Preparedness Innovations, is launching its call for proposals (CfP), open to all types of organisations able to advance vaccine candidates from the late pre-clinical stage through to Phase II for:

• MERS
• Lassa
• Nipah

With an initial investment of US$460m from the governments of Germany, Japan and Norway, plus the Bill & Melinda Gates Foundation and the Wellcome Trust, CEPI will seek to outsmart epidemics by developing safe and effective vaccines against known infectious disease threats that could be deployed rapidly to contain outbreaks, before they become global health emergencies.

The funding opportunity through this CfP is available worldwide to all types of private non-profit research organizations or for-profit multinational companies, including but not limited to small and medium sized biotechnology companies, international organizations and foundations, joint R&D ventures, government research and academic institutions.

The deadline for submission of preliminary proposals is 8 March 2017.

More information:  http://cepi.net/CfP

RSTMH 2016-17 grants round

We are delighted to announce that our new grants round is now open. RSTMH are pleased to be able to offer £100,000 in this new round of travel scholarships and small grants. 

Our aim is to support clinicians and scientists in all disciplines of tropical medicine and global health. This includes the relationship between human health and animal health, in the pursuit of themes of clinical or scientific research or fieldwork.

Our focus will be on the early-career investigator (maximum 15 years active relevant training or employment) with clear research plans, adequate supervision and institutional support and few alternative sources of funding.

We are particularly looking to fund projects with a strong element of creativity and/or innovation that will have benefits beyond the academic community and will make a tangible and measurable difference.

We will consider applications for travel and training scholarships (up to £1,000) and small grants (up to £5,000) such as pump-priming grants, pilot studies or discrete elements within larger projects.

Our regulations and application forms can be downloaded below. The deadline for submitting applications is 5pm BST/GMT on Friday 27 January 2017 and disbursements will be made from April onwards. 

Further information: https://rstmh.org/grants/2016-17-grants-round

Health Systems Research Initiative call 4

Providing evidence to strengthen health systems in Low- and Middle-Income Countries (LMICs)

• Closing date: 24 Jan 2017 16:00 GMT

The Department of International Development (DFID), the Economic and Social Research Council (ESRC), the Medical Research Council (MRC) and the Wellcome Trust (WT) jointly fund the Health Systems Research Initiative. All funders are committed to funding world-class research with high potential for impact on policy and practice.

Launched in 2013 this programme will generate world class and cutting-edge research that addresses key questions on strengthening and improving health systems in developing countries. Following an excellent response to this programme from the research community, funding has now been secured for an annual call under this initiative until 2021.

The programme’s aims are to fund methodologically rigorous, high quality research that will:

1. Generate evidence on how to strengthen and improve health systems for people living in low- and middle-income countries.

2. Use a health systems approach to inform the delivery of evidence-based interventions or structural changes. Proposals must demonstrate how interventions relate to and affect wider elements of a health system such as governance, financing, health workforce, information systems, service delivery etc.

3. Provide evidence that is of direct relevance to decision makers and practitioners in the field.

This is the fourth annual call for the Health Systems Research Initiative. Up to £6million is available for funding proposals under this call.  Innovative proposals are sought from across the public health, social and biomedical sciences and must clearly identify what health system challenge is being addressed. Proposals must situate this clearly-defined challenge within an understanding of the broader health system linkages and describe how and why findings from the project have the potential to improve the health of people living in low and middle-income countries. Funding is available for research only; we will not fund the routine delivery of health services.

Projects with Principal Investigators (P-Is) from LMICs are strongly encouraged and all proposals must include Co-Investigators from the LMIC in which the research is taking place. Principal investigators can be based in the UK or any LMIC.

Research Grants: (Applications for Research Grants will be subject to a 2 stage review process. Only those successful at the outline stage will be invited to submit a full application and final funding decisions will be made in October 2017). The duration of a Research Grant is usually up to 3 years, with a maximum duration of 5 years. Small and larger-scale projects are invited. As a guide, applicants should note there is approx. £4m available for Research Grants under this call. Funders would like to fund 5-10 projects. 

Foundation Grants: (Applications for Foundation Grants will be reviewed at the March 2017 panel meeting following which funding decisions will be announced). We anticipate the duration of foundation grants to be no longer than 24 months, with a maximum budget of £200k each. The purpose of a foundation grant is either:- (i) to conduct preliminary studies needed before a full research grant proposal can be designed, this can include work to evaluate existing interventions or pilot and feasibility work to inform plans for future research. (ii) to explore possible health system innovations, under researched areas or creative approaches that have the potential to be developed further, however such proposals should also have practical applications and should not be purely conceptual. Recipients of Foundation Grants will not automatically progress to full-scale research projects after their grant has ended. They will be expected to apply for a full-scale research project through the standard competitive process.

Link to additional information: https://www.mrc.ac.uk/funding/browse/health-systems-research-initiative-call-4/